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The Power of DPA

Seal Oil is with mother’s milk one of the rare natural source of DPA. Although DPA, EPA and DHA work together to ensure the proper functioning of the human body, scientific research has shown that DPA has unique advantages.

  • Supports cardiovascular health
  • Enhances mental & cognitive health
  • Fights inflammation
  • Boosts immune system
  • Fetal & infant development
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  • Supports cardiovascular health
  • Enhances mental & cognitive health
  • Fights inflammation
  • Boosts immune system
  • Fetal & infant development

What is DPA?

Docosapentaenoic acid (DPA) is an essential fatty acid, shown to reduce blood clotting aortic plaque build-up Kaur G, Cameron-Smith D, Garg M, Sinclair AJ. Docosapentaenoic acid (22:5n-3): a review of its biological effects. Prog Lipid Res. 2011 Jan;50(1):28-34. doi: 10.1016/j.plipres.2010.07.004. Epub 2010 Jul 23. PMID: 20655949., and inflammation, and improve neural health. It also interacts powerfully with DHA and EPA—two other key omega-3 essential fatty acids—enabling the body to better store, absorb, and use those crucial molecules.Byelashov, O. A., Sinclair, A. J., & Kaur, G. (2015). Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid. Lipid technology, 27(4), 79–82. https://doi.org/10.1002/lite.201500013

 

To get technical for a moment, DPA is a straight chain 22:5 polyunsaturated fatty acid (22 carbons, 5 double-bonds). It is found in oily fish, seafood, and beef in small quantities. Seal oil and breast milk, however, are rich in DPA. And that’s one key advantage seal oil supplements have over fish oil.

 

DPA is so valuable, in fact, a scientific research suggests the historically low rate of heart disease among northern Inuit populations is a direct result of the consumption of seal meat and blubber.Byelashov, O. A., Sinclair, A. J., & Kaur, G. (2015). Dietary sources, current intakes, and nutritional role of omega-3 docosapentaenoic acid. Lipid technology, 27(4), 79–82. https://doi.org/10.1002/lite.201500013

DPA vs. DHA vs. EPA

While their chemical structures differ, DPA (Docosapentaenoic acid), EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic Acid) are all essential polyunsaturated omega-3 fatty acids. They are termed essential because the human body needs them to function optimally—but the human body is not capable of producing sufficient amounts on its own. That means we have to access these nutrients through food or supplements.

 

These three omega-3 fatty acids work together to support the healthy functioning of our bodies, boosting heart health, joint health, brain health, and immune system function. As well, each has a specific role to play:

DPA

  • Repairs damaged vessels
  • Fights chronic inflammation
  • Improves lipid metabolism
  • Boosts absorption of EPA and DHA

 

DHA

  • Boosts brain function
  • Helps combat mood disorders
  • Improves ocular health
  • Important component of cell membrane structure

EPA

  • Supports cardiovascular health
  • Supports immune system function
  • Reduces joint inflammation
  • Lowers cholesterol

DPA benefits 1

An Omega-3 that absorbs better

A scientific study has shown that after 14 days of supplementation, the total level of Omega-3s in the body of those consuming seal oil was more than 20% greater compared to those consuming fish oil. Mann NJ, O’Connell SL, Baldwin KM, Singh I, Meyer BJ. Effects of seal oil and tuna-fish oil on platelet parameters and plasma lipid levels in healthy subjects. Lipids. 2010 Aug;45(8):669-81. doi: 10.1007/s11745-010-3450-z. Epub 2010 Jul 23. PMID: 20652432

DPA Benefits 3

10x more effective than EPA

Studies have shown that the same health results are achieved using just 1/10th the amount of DPA compared to EPA. Kanayasu-Toyoda T, Morita I, Murota S. Docosapentaenoic acid (22:5, n-3), an elongation metabolite of eicosapentaenoic acid (20:5, n-3), is a potent stimulator of endothelial cell migration on pretreatment in vitro. Prostaglandins Leukot Essent Fatty Acids. 1996 May;54(5):319-25. doi: 10.1016/s0952-3278(96)90045-9. PMID: 8832760.

DPA Benefits 4

Helps repair blood vessels

Data show that DPA helps to achieve maximal endothelial migration, a critical function in repairing blood vessels. Kaur G, Cameron-Smith D, Garg M, Sinclair AJ. Docosapentaenoic acid (22:5n-3): a review of its biological effects. Prog Lipid Res. 2011 Jan;50(1):28-34. doi: 10.1016/j.plipres.2010.07.004. Epub 2010 Jul 23. PMID: 20655949 Mann NJ, O’Connell SL, Baldwin KM, Singh I, Meyer BJ. Effects of seal oil and tuna-fish oil on platelet parameters and plasma lipid levels in healthy subjects. Lipids. 2010 Aug;45(8):669-81. doi: 10.1007/s11745-010-3450-z. Epub 2010 Jul 23. PMID: 20652432.

Boosts all key Omega-3’s

An interesting human clinical trial involved giving doses of concentrated DPA to a number of subjects. The study showed that, even after short-term supplementation with DPA, blood levels of EPA, DHA and DPA were all elevated. This study showed that unlike DPA, an EPA supplementation only increased the proportions of EPA in the body.  This indicates DPA acts as a “storage depot,” allowing the body to store and access these crucial omega-3s as needed. This optimizes absorption and utilization. Miller E, Kaur G, Larsen A, Loh SP, Linderborg K, Weisinger HS, Turchini GM, Cameron-Smith D, Sinclair AJ. A short-term n-3 DPA supplementation study in humans. Eur J Nutr. 2013 Apr;52(3):895-904. doi: 10.1007/s00394-012-0396-3. Epub 2012 Jun 23. PMID: 22729967.

DPA Benefits 2

The DPA ‘storage depot’

The full range of health benefits of DPA are only just beginning to be understood. Studies in mammals and cell cultures have underscored its value in fighting inflammation, improving blood vessel health and elasticity, reducing the risk of blood clots, and metabolising fats.

 

The evidence is mounting, and it’s clear: DPA is a powerful omega-3 with a host of benefits and it also improves the body’s use of other essential omega-3s. Choosing fish oil, or any other omega-3 supplement without DPA, is a missed opportunity for better overall wellbeing.

Oil

Oméga-3 d'huile de phoque pure

L'huile de phoque est une source complète d'oméga-3 (DPA + DHA + EPA) avec une absorption optimisée grâce à sa structure moléculaire provenant d'un mammifère.

Huile de phoqueHuile de phoque

Huile de phoque

Textile

Fourrure unique & naturelle

La fourrure de loup-marin est un matériel très polyvalent utilisé dans de multiples applications telles que les accessoires, les chaussures, les vêtements et la décoration.

FourrureFourrure

Fourrure

Meat

Wild Canadian Meat

Seal meat represents an excellent source of protein and is high in iron, zinc, magnesium and vitamin B-12. This wild game meat is free from antibiotics and added hormones.

Viande de phoqueViande de phoque

Viande de phoque

References